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Pleiotropic Mechanisms Indicated for Sex Differences in Autism

Sexual dimorphism in common disease is pervasive, including a dramatic male preponderance in autism spectrum disorders (ASDs). Potential genetic explanations include a liability threshold model requiring increased polymorphism risk in females, sex-limited X-chromosome contribution, gene-environment...

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Detalles Bibliográficos
Autores principales: Mitra, Ileena, Tsang, Kathryn, Ladd-Acosta, Christine, Croen, Lisa A., Aldinger, Kimberly A., Hendren, Robert L., Traglia, Michela, Lavillaureix, Alinoë, Zaitlen, Noah, Oldham, Michael C., Levitt, Pat, Nelson, Stanley, Amaral, David G., Herz-Picciotto, Irva, Fallin, M. Daniele, Weiss, Lauren A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147776/
https://www.ncbi.nlm.nih.gov/pubmed/27846226
http://dx.doi.org/10.1371/journal.pgen.1006425