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A Stochastic Model of the Yeast Cell Cycle Reveals Roles for Feedback Regulation in Limiting Cellular Variability

The cell division cycle of eukaryotes is governed by a complex network of cyclin-dependent protein kinases (CDKs) and auxiliary proteins that govern CDK activities. The control system must function reliably in the context of molecular noise that is inevitable in tiny yeast cells, because mistakes in...

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Detalles Bibliográficos
Autores principales: Barik, Debashis, Ball, David A., Peccoud, Jean, Tyson, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147779/
https://www.ncbi.nlm.nih.gov/pubmed/27935947
http://dx.doi.org/10.1371/journal.pcbi.1005230