Cargando…

Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5’-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway

Schistosoma mansoni do not have de novo purine pathways and rely on purine salvage for their purine supply. It has been demonstrated that, unlike humans, the S. mansoni is able to produce adenine directly from adenosine, although the enzyme responsible for this activity was unknown. In the present w...

Descripción completa

Detalles Bibliográficos
Autores principales: Torini, Juliana Roberta, Brandão-Neto, José, DeMarco, Ricardo, Pereira, Humberto D'Muniz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147791/
https://www.ncbi.nlm.nih.gov/pubmed/27935959
http://dx.doi.org/10.1371/journal.pntd.0005178