Sympathetic Hyperactivity, Increased Tyrosine Hydroxylase and Exaggerated Corpus Cavernosum Relaxations Associated with Oxidative Stress Plays a Major Role in the Penis Dysfunction in Townes Sickle Cell Mouse

BACKGROUND: Sickle cell disease patients display priapism that may progress to erectile dysfunction. However, little is known about the pathophysiological alterations of corpus cavernosum in sickle cell disease. OBJECTIVE: Thus, this study aimed to evaluate the functional and molecular alterations o...

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Detalles Bibliográficos
Autores principales: Silva, Fábio H., Claudino, Mário A., Calmasini, Fabiano B., Alexandre, Eduardo C., Franco-Penteado, Carla, Burnett, Arthur L., Antunes, Edson, Costa, Fernando F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147818/
https://www.ncbi.nlm.nih.gov/pubmed/27935981
http://dx.doi.org/10.1371/journal.pone.0166291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147818/
https://www.ncbi.nlm.nih.gov/pubmed/27935981
http://dx.doi.org/10.1371/journal.pone.0166291

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