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Hyperalgesia and Persistent Pain after Breast Cancer Surgery: A Prospective Randomized Controlled Trial with Perioperative COX-2 Inhibition

BACKGROUND: Persistent pain is a challenging clinical problem after breast cancer treatment. After surgery, inflammatory pain and nociceptive input from nerve injury induce central sensitization which may play a role in the genesis of persistent pain. Using quantitative sensory testing, we tested th...

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Detalles Bibliográficos
Autores principales: van Helmond, Noud, Steegers, Monique A., Filippini-de Moor, Gertie P., Vissers, Kris C., Wilder-Smith, Oliver H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147830/
https://www.ncbi.nlm.nih.gov/pubmed/27935990
http://dx.doi.org/10.1371/journal.pone.0166601