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Hyperalgesia and Persistent Pain after Breast Cancer Surgery: A Prospective Randomized Controlled Trial with Perioperative COX-2 Inhibition
BACKGROUND: Persistent pain is a challenging clinical problem after breast cancer treatment. After surgery, inflammatory pain and nociceptive input from nerve injury induce central sensitization which may play a role in the genesis of persistent pain. Using quantitative sensory testing, we tested th...
Autores principales: | van Helmond, Noud, Steegers, Monique A., Filippini-de Moor, Gertie P., Vissers, Kris C., Wilder-Smith, Oliver H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147830/ https://www.ncbi.nlm.nih.gov/pubmed/27935990 http://dx.doi.org/10.1371/journal.pone.0166601 |
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