A Biodegradable Polyethylenimine-Based Vector Modified by Trifunctional Peptide R18 for Enhancing Gene Transfection Efficiency In Vivo

Lack of capacity to cross the nucleus membrane seems to be one of the main reasons for the lower transfection efficiency of gene vectors observed in vivo study than in vitro. To solve this problem, a new non-viral gene vector was designed. First, a degradable polyethylenimine (PEI) derivate was synt...

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Detalles Bibliográficos
Autores principales: Hu, Jing, Zhu, Manman, Liu, Kehai, Fan, Hua, Zhao, Wenfang, Mao, Yuan, Zhang, Yaguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147860/
https://www.ncbi.nlm.nih.gov/pubmed/27935984
http://dx.doi.org/10.1371/journal.pone.0166673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147860/
https://www.ncbi.nlm.nih.gov/pubmed/27935984
http://dx.doi.org/10.1371/journal.pone.0166673

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