Cargando…

The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions

RAS effectors specifically interact with the GTP-bound form of RAS in response to extracellular signals and link them to downstream signaling pathways. The molecular nature of effector interaction by RAS is well-studied but yet still incompletely understood in a comprehensive and systematic way. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakhaeizadeh, Hossein, Amin, Ehsan, Nakhaei-Rad, Saeideh, Dvorsky, Radovan, Ahmadian, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147862/
https://www.ncbi.nlm.nih.gov/pubmed/27936046
http://dx.doi.org/10.1371/journal.pone.0167145