Cargando…
The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions
RAS effectors specifically interact with the GTP-bound form of RAS in response to extracellular signals and link them to downstream signaling pathways. The molecular nature of effector interaction by RAS is well-studied but yet still incompletely understood in a comprehensive and systematic way. Her...
Autores principales: | Nakhaeizadeh, Hossein, Amin, Ehsan, Nakhaei-Rad, Saeideh, Dvorsky, Radovan, Ahmadian, Mohammad Reza |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147862/ https://www.ncbi.nlm.nih.gov/pubmed/27936046 http://dx.doi.org/10.1371/journal.pone.0167145 |
Ejemplares similares
-
New mechanistic insights into the RAS-SIN1 interaction at the membrane
por: Pudewell, Silke, et al.
Publicado: (2022) -
A comprehensive analysis of RAS-effector interactions reveals interaction hotspots and new binding partners
por: Rezaei Adariani, Soheila, et al.
Publicado: (2021) -
Editorial: Identifying the isoform-specific roles of RAS paralogs in health and disease
por: Nakhaei-Rad, Saeideh, et al.
Publicado: (2023) -
Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclustering
por: Blaževitš, Olga, et al.
Publicado: (2016) -
Specific Conformational
States of Ras GTPase upon
Effector Binding
por: Baussand, Julie, et al.
Publicado: (2012)