A High-Throughput Strategy for Dissecting Mammalian Genetic Interactions

Comprehensive delineation of complex cellular networks requires high-throughput interrogation of genetic interactions. To address this challenge, we describe the development of a multiplex combinatorial strategy to assess pairwise genetic interactions using CRISPR-Cas9 genome editing and next-genera...

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Detalles Bibliográficos
Autores principales: Stockman, Victoria B., Ghamsari, Lila, Lasso, Gorka, Honig, Barry, Shapira, Sagi D., Wang, Harris H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147906/
https://www.ncbi.nlm.nih.gov/pubmed/27936040
http://dx.doi.org/10.1371/journal.pone.0167617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147906/
https://www.ncbi.nlm.nih.gov/pubmed/27936040
http://dx.doi.org/10.1371/journal.pone.0167617

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