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A High-Throughput Strategy for Dissecting Mammalian Genetic Interactions

Comprehensive delineation of complex cellular networks requires high-throughput interrogation of genetic interactions. To address this challenge, we describe the development of a multiplex combinatorial strategy to assess pairwise genetic interactions using CRISPR-Cas9 genome editing and next-genera...

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Detalles Bibliográficos
Autores principales:	Stockman, Victoria B., Ghamsari, Lila, Lasso, Gorka, Honig, Barry, Shapira, Sagi D., Wang, Harris H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147906/ https://www.ncbi.nlm.nih.gov/pubmed/27936040 http://dx.doi.org/10.1371/journal.pone.0167617

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