Ophiobolin A Induces Autophagy and Activates the Mitochondrial Pathway of Apoptosis in Human Melanoma Cells

Ophiobolin A, a fungal toxin from Bipolaris species known to affect different cellular processes in plants, has recently been shown to have anti-cancer activity in mammalian cells. In the present study, we investigated the anti-proliferative effect of Ophiobolin A on human melanoma A375 and CHL-1 ce...

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Detalles Bibliográficos
Autores principales: Rodolfo, Carlo, Rocco, Mariapina, Cattaneo, Lucia, Tartaglia, Maria, Sassi, Mauro, Aducci, Patrizia, Scaloni, Andrea, Camoni, Lorenzo, Marra, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147944/
https://www.ncbi.nlm.nih.gov/pubmed/27936075
http://dx.doi.org/10.1371/journal.pone.0167672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147944/
https://www.ncbi.nlm.nih.gov/pubmed/27936075
http://dx.doi.org/10.1371/journal.pone.0167672

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