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Increased Age, but Not Parity Predisposes to Higher Bacteriuria Burdens Due to Streptococcus Urinary Tract Infection and Influences Bladder Cytokine Responses, Which Develop Independent of Tissue Bacterial Loads

Streptococcus agalactiae causes urinary tract infection (UTI) in pregnant adults, non-pregnant adults, immune-compromised individuals and the elderly. The pathogenesis of S. agalactiae UTI in distinct patient populations is poorly understood. In this study, we used murine models of UTI incorporating...

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Detalles Bibliográficos
Autores principales: Sullivan, Matthew J., Carey, Alison J., Leclercq, Sophie Y., Tan, Chee K., Ulett, Glen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147962/
https://www.ncbi.nlm.nih.gov/pubmed/27936166
http://dx.doi.org/10.1371/journal.pone.0167732