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Development of Serum Marker Models to Increase Diagnostic Accuracy of Advanced Fibrosis in Nonalcoholic Fatty Liver Disease: The New LINKI Algorithm Compared with Established Algorithms

BACKGROUND AND AIM: Detection of advanced fibrosis (F3-F4) in nonalcoholic fatty liver disease (NAFLD) is important for ascertaining prognosis. Serum markers have been proposed as alternatives to biopsy. We attempted to develop a novel algorithm for detection of advanced fibrosis based on a more eff...

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Detalles Bibliográficos
Autores principales: Lykiardopoulos, Byron, Hagström, Hannes, Fredrikson, Mats, Ignatova, Simone, Stål, Per, Hultcrantz, Rolf, Ekstedt, Mattias, Kechagias, Stergios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147971/
https://www.ncbi.nlm.nih.gov/pubmed/27936091
http://dx.doi.org/10.1371/journal.pone.0167776