Hyperhomocysteinemia in ApoE-/- Mice Leads to Overexpression of Enhancer of Zeste Homolog 2 via miR-92a Regulation

Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular diseases, such as atherosclerosis. HHcy promotes atherogenesis by modifying the histone methylation patterns and miRNA regulation. In this study, we investigated the effects of homocysteine (Hcy) on the expression of enhanc...

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Detalles Bibliográficos
Autores principales: Xiaoling, Yang, Li, Zhao, ShuQiang, Li, Shengchao, Ma, Anning, Yang, Ning, Ding, Nan, Li, Yuexia, Jia, Xiaoming, Yang, Guizhong, Li, Yideng, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147974/
https://www.ncbi.nlm.nih.gov/pubmed/27936205
http://dx.doi.org/10.1371/journal.pone.0167744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147974/
https://www.ncbi.nlm.nih.gov/pubmed/27936205
http://dx.doi.org/10.1371/journal.pone.0167744

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