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Application of a low molecular weight antifungal protein from Penicillium chrysogenum (PAF) to treat pulmonary aspergillosis in mice

PAF, a small antifungal protein from Penicillium chrysogenum, inhibits the growth of several pathogenic filamentous fungi, including members of the Aspergillus genus. PAF has been proven to have no toxic effects in vivo in mice by intranasal application. To test its efficacy against invasive pulmona...

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Detalles Bibliográficos
Autores principales: Palicz, Zoltán, Gáll, Tamás, Leiter, Éva, Kollár, Sándor, Kovács, Ilona, Miszti-Blasius, Kornél, Pócsi, István, Csernoch, László, Szentesi, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148020/
https://www.ncbi.nlm.nih.gov/pubmed/27826143
http://dx.doi.org/10.1038/emi.2016.116