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Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner

The membrane-associated serine proteases matriptase and prostasin are believed to function in close partnership. Their zymogen activation has been reported to be tightly coupled, either as a matriptase-initiated proteolytic cascade or through a mutually dependent mechanism involving the formation of...

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Detalles Bibliográficos
Autores principales: Su, Hui Chen, Liang, Yan A., Lai, Ying-Jung J., Chiu, Yi-Lin, Barndt, Robert B., Shiao, Frank, Chang, Hsiang-Hua D., Lu, Dajun D., Huang, Nanxi, Tseng, Chun-Che, Wang, Jehng-Kang, Lee, Ming-Shyue, Johnson, Michael D., Huang, Shih-Ming, Lin, Chen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148038/
https://www.ncbi.nlm.nih.gov/pubmed/27936035
http://dx.doi.org/10.1371/journal.pone.0167894