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Transgenic mouse model of IgM(+) lymphoproliferative disease mimicking Waldenström macroglobulinemia

Waldenström macroglobulinemia (WM) is a low-grade incurable immunoglobulin M(+) (IgM(+)) lymphoplasmacytic lymphoma for which a genetically engineered mouse model of de novo tumor development is lacking. On the basis of evidence that the pro-inflammatory cytokine, interleukin 6 (IL6), and the surviv...

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Detalles Bibliográficos
Autores principales: Tompkins, V S, Sompallae, R, Rosean, T R, Walsh, S, Acevedo, M, Kovalchuk, A L, Han, S-S, Jing, X, Holman, C, Rehg, J E, Herms, S, Sunderland, J S, Morse, H C, Janz, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148059/
https://www.ncbi.nlm.nih.gov/pubmed/27813533
http://dx.doi.org/10.1038/bcj.2016.95