Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion

BACKGROUND & AIMS: Developmental morphogens play an important role in coordinating the ductular reaction and portal fibrosis occurring in the setting of cholangiopathies. However, little is known about how membrane signaling events in ductular reactive cells (DRCs) are transduced into nuclear tr...

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Detalles Bibliográficos
Autores principales: Jalan-Sakrikar, Nidhi, De Assuncao, Thiago M., Lu, Jie, Almada, Luciana L., Lomberk, Gwen, Fernandez-Zapico, Martin E., Urrutia, Raul, Huebert, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148157/
https://www.ncbi.nlm.nih.gov/pubmed/27936185
http://dx.doi.org/10.1371/journal.pone.0168266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148157/
https://www.ncbi.nlm.nih.gov/pubmed/27936185
http://dx.doi.org/10.1371/journal.pone.0168266

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