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Using the Amino Acid Network to Modulate the Hydrolytic Activity of β-Glycosidases
The active site residues in GH1 β-glycosidases are compartmentalized into 3 functional regions, involved in catalysis or binding of glycone and aglycone motifs from substrate. However, it still remains unclear how residues outside the active site modulate the enzymatic activity. To tackle this quest...
Autores principales: | Tamaki, Fábio K., Souza, Diorge P., Souza, Valquiria P., Ikegami, Cecilia M., Farah, Chuck S., Marana, Sandro R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148593/ https://www.ncbi.nlm.nih.gov/pubmed/27936116 http://dx.doi.org/10.1371/journal.pone.0167978 |
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