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BRAF activates PAX3 to control muscle precursor cell migration during forelimb muscle development

Migration of skeletal muscle precursor cells is a key step during limb muscle development and depends on the activity of PAX3 and MET. Here, we demonstrate that BRAF serves a crucial function in formation of limb skeletal muscles during mouse embryogenesis downstream of MET and acts as a potent indu...

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Detalles Bibliográficos
Autores principales: Shin, Jaeyoung, Watanabe, Shuichi, Hoelper, Soraya, Krüger, Marcus, Kostin, Sawa, Pöling, Jochen, Kubin, Thomas, Braun, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148607/
https://www.ncbi.nlm.nih.gov/pubmed/27906130
http://dx.doi.org/10.7554/eLife.18351