Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

Mesenchymal stem cell (MSC) differentiation is mediated by soluble and physical cues. In this study, we investigated differentiation-induced transformations in MSC cellular and nuclear biophysical properties and queried their role in mechanosensation. Our data show that nuclei in differentiated bovi...

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Detalles Bibliográficos
Autores principales: Heo, Su-Jin, Driscoll, Tristan P, Thorpe, Stephen D, Nerurkar, Nandan L, Baker, Brendon M, Yang, Michael T, Chen, Christopher S, Lee, David A, Mauck, Robert L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148611/
https://www.ncbi.nlm.nih.gov/pubmed/27901466
http://dx.doi.org/10.7554/eLife.18207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148611/
https://www.ncbi.nlm.nih.gov/pubmed/27901466
http://dx.doi.org/10.7554/eLife.18207

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