Cargando…
Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity
Mesenchymal stem cell (MSC) differentiation is mediated by soluble and physical cues. In this study, we investigated differentiation-induced transformations in MSC cellular and nuclear biophysical properties and queried their role in mechanosensation. Our data show that nuclei in differentiated bovi...
Autores principales: | Heo, Su-Jin, Driscoll, Tristan P, Thorpe, Stephen D, Nerurkar, Nandan L, Baker, Brendon M, Yang, Michael T, Chen, Christopher S, Lee, David A, Mauck, Robert L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148611/ https://www.ncbi.nlm.nih.gov/pubmed/27901466 http://dx.doi.org/10.7554/eLife.18207 |
Ejemplares similares
-
Mechano-adaptation of the stem cell nucleus
por: Heo, Su-Jin, et al.
Publicado: (2017) -
Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells
por: Heo, Su-Jin, et al.
Publicado: (2015) -
Rod nuclear architecture determines contrast transmission of the retina and behavioral sensitivity in mice
por: Subramanian, Kaushikaram, et al.
Publicado: (2019) -
Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance
por: Baba, Kentarou, et al.
Publicado: (2018) -
A mechano-osmotic feedback couples cell volume to the rate of cell deformation
por: Venkova, Larisa, et al.
Publicado: (2022)