Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells

The natural flavonoid quercetin is known to activate the transcription factor Nrf2, which regulates the expression of cytoprotective enzymes such as heme oxygenase-1 (HO-1) and NAD(P)H:quinone oxidoreductase 1 (NQO1). In this study, a novel semisynthetic flavonoid 7-O-galloylquercetin (or quercetin-...

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Detalles Bibliográficos
Autores principales: Roubalová, Lenka, Biedermann, David, Papoušková, Barbora, Vacek, Jan, Kuzma, Marek, Křen, Vladimír, Ulrichová, Jitka, Dinkova-Kostova, Albena T., Vrba, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148792/
https://www.ncbi.nlm.nih.gov/pubmed/27777014
http://dx.doi.org/10.1016/j.cbi.2016.10.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148792/
https://www.ncbi.nlm.nih.gov/pubmed/27777014
http://dx.doi.org/10.1016/j.cbi.2016.10.015

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