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Antiestrogens: structure-activity relationships and use in breast cancer treatment

About 70% of breast tumors express estrogen receptor alpha (ERα), which mediates the proliferative effects of estrogens on breast epithelial cells, and are candidates for treatment with antiestrogens, steroidal or non-steroidal molecules designed to compete with estrogens and antagonize ERs. The var...

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Detalles Bibliográficos
Autores principales: Traboulsi, T, El Ezzy, M, Gleason, J L, Mader, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148801/
https://www.ncbi.nlm.nih.gov/pubmed/27729460
http://dx.doi.org/10.1530/JME-16-0024