Single Nucleotide Polymorphism–Based Validation of Exonic Splicing Enhancers

Because deleterious alleles arising from mutation are filtered by natural selection, mutations that create such alleles will be underrepresented in the set of common genetic variation existing in a population at any given time. Here, we describe an approach based on this idea called VERIFY (variant...

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Detalles Bibliográficos
Autores principales: Fairbrother, William G, Holste, Dirk, Burge, Christopher B, Sharp, Phillip A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514884/
https://www.ncbi.nlm.nih.gov/pubmed/15340491
http://dx.doi.org/10.1371/journal.pbio.0020268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514884/
https://www.ncbi.nlm.nih.gov/pubmed/15340491
http://dx.doi.org/10.1371/journal.pbio.0020268

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