Cargando…

High glucose suppresses embryonic stem cell differentiation into cardiomyocytes: High glucose inhibits ES cell cardiogenesis

BACKGROUND: Babies born to mothers with pregestational diabetes have a high risk for congenital heart defects (CHD). Embryonic stem cells (ESCs) are excellent in vitro models for studying the effect of high glucose on cardiac lineage specification because ESCs can be differentiated into cardiomyocyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Penghua, Chen, Xi, Kaushal, Sunjay, Reece, E. Albert, Yang, Peixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148851/
https://www.ncbi.nlm.nih.gov/pubmed/27938398
http://dx.doi.org/10.1186/s13287-016-0446-5