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High glucose suppresses embryonic stem cell differentiation into cardiomyocytes: High glucose inhibits ES cell cardiogenesis
BACKGROUND: Babies born to mothers with pregestational diabetes have a high risk for congenital heart defects (CHD). Embryonic stem cells (ESCs) are excellent in vitro models for studying the effect of high glucose on cardiac lineage specification because ESCs can be differentiated into cardiomyocyt...
Autores principales: | Yang, Penghua, Chen, Xi, Kaushal, Sunjay, Reece, E. Albert, Yang, Peixin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148851/ https://www.ncbi.nlm.nih.gov/pubmed/27938398 http://dx.doi.org/10.1186/s13287-016-0446-5 |
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