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Metalloproteinases and their inhibitors are influenced by inhalative glucocorticoid therapy in combination with environmental dust reduction in equine recurrent airway obstruction

BACKGROUND: Overexpression of matrix-metalloproteinases (MMPs) has been shown to lead to tissue damage in equine recurrent airway obstruction (RAO), as a misbalance with their natural inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), occurs. This favors irreversible pulmonary fibrosis...

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Detalles Bibliográficos
Autores principales: Barton, Ann Kristin, Shety, Tarek, Bondzio, Angelika, Einspanier, Ralf, Gehlen, Heidrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148864/
https://www.ncbi.nlm.nih.gov/pubmed/27938355
http://dx.doi.org/10.1186/s12917-016-0915-1