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Metalloproteinases and their inhibitors are influenced by inhalative glucocorticoid therapy in combination with environmental dust reduction in equine recurrent airway obstruction
BACKGROUND: Overexpression of matrix-metalloproteinases (MMPs) has been shown to lead to tissue damage in equine recurrent airway obstruction (RAO), as a misbalance with their natural inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), occurs. This favors irreversible pulmonary fibrosis...
Autores principales: | Barton, Ann Kristin, Shety, Tarek, Bondzio, Angelika, Einspanier, Ralf, Gehlen, Heidrun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148864/ https://www.ncbi.nlm.nih.gov/pubmed/27938355 http://dx.doi.org/10.1186/s12917-016-0915-1 |
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