3D culture models of Alzheimer’s disease: a road map to a “cure-in-a-dish”

Alzheimer’s disease (AD) transgenic mice have been used as a standard AD model for basic mechanistic studies and drug discovery. These mouse models showed symbolic AD pathologies including β-amyloid (Aβ) plaques, gliosis and memory deficits but failed to fully recapitulate AD pathogenic cascades inc...

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Detalles Bibliográficos
Autores principales: Choi, Se Hoon, Kim, Young Hye, Quinti, Luisa, Tanzi, Rudolph E., Kim, Doo Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148918/
https://www.ncbi.nlm.nih.gov/pubmed/27938410
http://dx.doi.org/10.1186/s13024-016-0139-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148918/
https://www.ncbi.nlm.nih.gov/pubmed/27938410
http://dx.doi.org/10.1186/s13024-016-0139-7

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