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Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Models
RATIONALE: Vascular smooth muscle cell (VSMC) accumulation is a hallmark of atherosclerosis and vascular injury. However, fundamental aspects of proliferation and the phenotypic changes within individual VSMCs, which underlie vascular disease, remain unresolved. In particular, it is not known whethe...
Autores principales: | Chappell, Joel, Harman, Jennifer L., Narasimhan, Vagheesh M., Yu, Haixiang, Foote, Kirsty, Simons, Benjamin D., Bennett, Martin R., Jørgensen, Helle F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149073/ https://www.ncbi.nlm.nih.gov/pubmed/27682618 http://dx.doi.org/10.1161/CIRCRESAHA.116.309799 |
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