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Random‐effects meta‐analysis for systematic reviews of phase I clinical trials: Rare events and missing data
Phase I trials aim to establish appropriate clinical and statistical parameters to guide future clinical trials. With individual trials typically underpowered, systematic reviews and meta‐analysis are desired to assess the totality of evidence. A high percentage of zero or missing outcomes often com...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149121/ https://www.ncbi.nlm.nih.gov/pubmed/27285532 http://dx.doi.org/10.1002/jrsm.1209 |