Cargando…

Random‐effects meta‐analysis for systematic reviews of phase I clinical trials: Rare events and missing data

Phase I trials aim to establish appropriate clinical and statistical parameters to guide future clinical trials. With individual trials typically underpowered, systematic reviews and meta‐analysis are desired to assess the totality of evidence. A high percentage of zero or missing outcomes often com...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Mi‐Ok, Wang, Xia, Liu, Chunyan, Dorris, Kathleen, Fouladi, Maryam, Song, Seongho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149121/
https://www.ncbi.nlm.nih.gov/pubmed/27285532
http://dx.doi.org/10.1002/jrsm.1209