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Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle

Sox6 belongs to the Sox gene family and plays a pivotal role in fiber type differentiation, suppressing transcription of slow-fiber-specific genes during fetal development. Here, we show that Sox6 plays opposite roles in MyHC-I regulation, acting as a positive and negative regulator of MyHC-I expres...

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Detalles Bibliográficos
Autores principales: Taglietti, Valentina, Maroli, Giovanni, Cermenati, Solei, Monteverde, Stefania, Ferrante, Andrea, Rossi, Giuliana, Cossu, Giulio, Beltrame, Monica, Messina, Graziella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149531/
https://www.ncbi.nlm.nih.gov/pubmed/27880909
http://dx.doi.org/10.1016/j.celrep.2016.10.082