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Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle
Sox6 belongs to the Sox gene family and plays a pivotal role in fiber type differentiation, suppressing transcription of slow-fiber-specific genes during fetal development. Here, we show that Sox6 plays opposite roles in MyHC-I regulation, acting as a positive and negative regulator of MyHC-I expres...
Autores principales: | Taglietti, Valentina, Maroli, Giovanni, Cermenati, Solei, Monteverde, Stefania, Ferrante, Andrea, Rossi, Giuliana, Cossu, Giulio, Beltrame, Monica, Messina, Graziella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149531/ https://www.ncbi.nlm.nih.gov/pubmed/27880909 http://dx.doi.org/10.1016/j.celrep.2016.10.082 |
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