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SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis

Actin plays a critical role during the early stages of pathogenic microbe internalization by immune cells. In this study, we identified a key mechanism of actin filament tethering and stabilization to the surface of phagosomes in human dendritic cells. We found that the actin-binding protein SWAP70...

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Detalles Bibliográficos
Autores principales: Baranov, Maksim V., Revelo, Natalia H., Dingjan, Ilse, Maraspini, Riccardo, ter Beest, Martin, Honigmann, Alf, van den Bogaart, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149533/
https://www.ncbi.nlm.nih.gov/pubmed/27806292
http://dx.doi.org/10.1016/j.celrep.2016.10.021