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The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem

Several important and fundamental aspects of disease genetics models have yet to be described. One such property is the relationship of disease association statistics at a marker site closely linked to a disease causing site. A complete description of this two-locus system is of particular importanc...

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Detalles Bibliográficos
Autores principales: Maadooliat, Mehdi, Bansal, Naveen K., Upadhya, Jiblal, Farazi, Manzur R., Li, Xiang, He, Max M., Hebbring, Scott J., Ye, Zhan, Schrodi, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149547/
https://www.ncbi.nlm.nih.gov/pubmed/28018425
http://dx.doi.org/10.3389/fgene.2016.00217