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The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem
Several important and fundamental aspects of disease genetics models have yet to be described. One such property is the relationship of disease association statistics at a marker site closely linked to a disease causing site. A complete description of this two-locus system is of particular importanc...
Autores principales: | Maadooliat, Mehdi, Bansal, Naveen K., Upadhya, Jiblal, Farazi, Manzur R., Li, Xiang, He, Max M., Hebbring, Scott J., Ye, Zhan, Schrodi, Steven J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149547/ https://www.ncbi.nlm.nih.gov/pubmed/28018425 http://dx.doi.org/10.3389/fgene.2016.00217 |
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