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N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics
N-Myc is a global transcription factor that regulates the expression of genes involved in a number of essential cellular processes including: ribosome biogenesis, cell cycle and apoptosis. Upon deregulation, N-Myc can drive pathologic expression of many of these genes, which ultimately defines its o...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149579/ https://www.ncbi.nlm.nih.gov/pubmed/28028439 http://dx.doi.org/10.1038/cddiscovery.2016.82 |