N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics

N-Myc is a global transcription factor that regulates the expression of genes involved in a number of essential cellular processes including: ribosome biogenesis, cell cycle and apoptosis. Upon deregulation, N-Myc can drive pathologic expression of many of these genes, which ultimately defines its o...

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Detalles Bibliográficos
Autores principales: Casinelli, Gabriella, LaRosa, Jeff, Sharma, Manika, Cherok, Edward, Banerjee, Swati, Branca, Maria, Edmunds, Lia, Wang, Yudong, Sims-Lucas, Sunder, Churley, Luke, Kelly, Samantha, Sun, Ming, Stolz, Donna, Graves, J Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149579/
https://www.ncbi.nlm.nih.gov/pubmed/28028439
http://dx.doi.org/10.1038/cddiscovery.2016.82

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