Exome Sequencing Identifies Compound Heterozygous Mutations in SCN5A Associated with Congenital Complete Heart Block in the Thai Population

Background. Congenital heart block is characterized by blockage of electrical impulses from the atrioventricular node (AV node) to the ventricles. This blockage can be caused by ion channel impairment that is the result of genetic variation. This study aimed to investigate the possible causative var...

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Detalles Bibliográficos
Autores principales: Thongnak, Chuphong, Limprasert, Pornprot, Tangviriyapaiboon, Duangkamol, Silvilairat, Suchaya, Puangpetch, Apichaya, Pasomsub, Ekawat, Sukasem, Chonlaphat, Chantratita, Wasun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149683/
https://www.ncbi.nlm.nih.gov/pubmed/28018021
http://dx.doi.org/10.1155/2016/3684965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149683/
https://www.ncbi.nlm.nih.gov/pubmed/28018021
http://dx.doi.org/10.1155/2016/3684965

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