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Combined MSC and GLP-1 Therapy Modulates Collagen Remodeling and Apoptosis following Myocardial Infarction

Background. Mesenchymal stem cells (MSCs) and glucagon-like peptide-1 (GLP-1) are being tested as treatment strategies for myocardial infarction (MI); however, their mechanisms in the heart are not fully understood. Methods. We examined the effects of MSCs, either native, or engineered to secrete a...

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Detalles Bibliográficos
Autores principales: Wright, Elizabeth J., Hodson, Nigel W., Sherratt, Michael J., Kassem, Moustapha, Lewis, Andrew L., Wallrapp, Christine, Malik, Nadim, Holt, Cathy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149702/
https://www.ncbi.nlm.nih.gov/pubmed/28003833
http://dx.doi.org/10.1155/2016/7357096