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SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model

Sepsis often results in damage to multiple organ systems, possibly due to severe mitochondrial dysfunction. Two members of the sirtuin family, SIRT1 and SIRT3, have been implicated in the reversal of mitochondrial damage. The aim of this study was to determine the role of SIRT1/3 in acute kidney inj...

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Detalles Bibliográficos
Autores principales: Xu, Siqi, Gao, Youguang, Zhang, Qin, Wei, Siwei, Chen, Zhongqing, Dai, Xingui, Zeng, Zhenhua, Zhao, Ke-seng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149703/
https://www.ncbi.nlm.nih.gov/pubmed/28003866
http://dx.doi.org/10.1155/2016/7296092