Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction

Hsp70 chaperones assist de novo folding of newly synthesized proteins in all cells. In yeast, the specialized Hsp70 Ssb directly binds to ribosomes. The structural basis and functional mode of recruitment of Ssb to ribosomes is not understood. Here, we present the molecular details underlying riboso...

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Detalles Bibliográficos
Autores principales: Hanebuth, Marie A., Kityk, Roman, Fries, Sandra J., Jain, Alok, Kriel, Allison, Albanese, Veronique, Frickey, Tancred, Peter, Christine, Mayer, Matthias P., Frydman, Judith, Deuerling, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150220/
https://www.ncbi.nlm.nih.gov/pubmed/27917864
http://dx.doi.org/10.1038/ncomms13695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150220/
https://www.ncbi.nlm.nih.gov/pubmed/27917864
http://dx.doi.org/10.1038/ncomms13695

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