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Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction
Hsp70 chaperones assist de novo folding of newly synthesized proteins in all cells. In yeast, the specialized Hsp70 Ssb directly binds to ribosomes. The structural basis and functional mode of recruitment of Ssb to ribosomes is not understood. Here, we present the molecular details underlying riboso...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150220/ https://www.ncbi.nlm.nih.gov/pubmed/27917864 http://dx.doi.org/10.1038/ncomms13695 |