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Potentiation of Amitriptyline Anti-Hyperalgesic-Like Action By Astroglial Connexin 43 Inhibition in Neuropathic Rats

Antidepressants, prescribed as first line treatment of neuropathic pain, have a limited efficacy and poorly tolerated side effects. Because recent studies pointed out the implication of astroglial connexins (Cx) in both neuropathic pain and antidepressive treatment, we investigated whether their blo...

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Detalles Bibliográficos
Autores principales: Jeanson, Tiffany, Duchêne, Adeline, Richard, Damien, Bourgoin, Sylvie, Picoli, Christèle, Ezan, Pascal, Mouthon, Franck, Giaume, Christian, Hamon, Michel, Charvériat, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150232/
https://www.ncbi.nlm.nih.gov/pubmed/27941941
http://dx.doi.org/10.1038/srep38766