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Potentiation of Amitriptyline Anti-Hyperalgesic-Like Action By Astroglial Connexin 43 Inhibition in Neuropathic Rats
Antidepressants, prescribed as first line treatment of neuropathic pain, have a limited efficacy and poorly tolerated side effects. Because recent studies pointed out the implication of astroglial connexins (Cx) in both neuropathic pain and antidepressive treatment, we investigated whether their blo...
Autores principales: | Jeanson, Tiffany, Duchêne, Adeline, Richard, Damien, Bourgoin, Sylvie, Picoli, Christèle, Ezan, Pascal, Mouthon, Franck, Giaume, Christian, Hamon, Michel, Charvériat, Mathieu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150232/ https://www.ncbi.nlm.nih.gov/pubmed/27941941 http://dx.doi.org/10.1038/srep38766 |
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