Nuclear Factor Erythroid 2-related Factor 2 Deficiency Exacerbates Lupus Nephritis in B6/lpr mice by Regulating Th17 Cell Function

Lupus nephritis (LN) is the major clinical manifestation of systemic lupus erythematosus. LN is promoted by T helper 17 (Th17) cells, which are the major pro-inflammatory T cell subset contributing to autoimmunity regulation. Nuclear factor erythroid 2-related factor 2 (NRF2) is critical for suppres...

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Detalles Bibliográficos
Autores principales: Zhao, Mei, Chen, Huanpeng, Ding, Qingfeng, Xu, Xiaoxie, Yu, Bolan, Huang, Zhaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150244/
https://www.ncbi.nlm.nih.gov/pubmed/27941837
http://dx.doi.org/10.1038/srep38619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150244/
https://www.ncbi.nlm.nih.gov/pubmed/27941837
http://dx.doi.org/10.1038/srep38619

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