Dihydroartemisinin inhibits catabolism in rat chondrocytes by activating autophagy via inhibition of the NF-κB pathway

Osteoarthritis is a disease with inflammatory and catabolic imbalance in cartilage. Dihydroartemisinin (DHA), a natural and safe anti-malarial agent, has been reported to inhibit inflammation, but its effects on chondrocytes have yet to be elucidated. We investigated the effects of DHA on catabolism...

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Detalles Bibliográficos
Autores principales: Jiang, Li-Bo, Meng, De-Hua, Lee, Soo-Min, Liu, Shu-Hao, Xu, Qin-Tong, Wang, Yang, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150254/
https://www.ncbi.nlm.nih.gov/pubmed/27941926
http://dx.doi.org/10.1038/srep38979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150254/
https://www.ncbi.nlm.nih.gov/pubmed/27941926
http://dx.doi.org/10.1038/srep38979

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