Multiplex CRISPR/Cas9-based genome engineering enhanced by Drosha-mediated sgRNA-shRNA structure

The clustered regularly interspaced short palindromic repeats (CRISPR) system has recently been developed into a powerful genome-editing technology, as it requires only two key components (Cas9 protein and sgRNA) to function and further enables multiplex genome targeting and homology-directed repair...

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Detalles Bibliográficos
Autores principales: Yan, Qiang, Xu, Kun, Xing, Jiani, Zhang, Tingting, Wang, Xin, Wei, Zehui, Ren, Chonghua, Liu, Zhongtian, Shao, Simin, Zhang, Zhiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150520/
https://www.ncbi.nlm.nih.gov/pubmed/27941919
http://dx.doi.org/10.1038/srep38970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150520/
https://www.ncbi.nlm.nih.gov/pubmed/27941919
http://dx.doi.org/10.1038/srep38970

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